Homocysteine Modulating Complex (60 Capsules) by Pharmax

  • High levels of folic acid proven to reduce plasma homocysteine level
  • Vitamin B12 and Vitamin B6 ensure consistent and balanced reduction in homocysteine level
  • Supplementation of betaine hydrochloride completes the cycle of methionine metabolism
  • Appropriate for all individuals with high risk of developing atherosclerosis and heart disease.*
  • Sug. Price:$37.05
    Our Price:$33.34
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  • High levels of folic acid proven to reduce plasma homocysteine level
  • Vitamin B12 and Vitamin B6 ensure consistent and balanced reduction in homocysteine level
  • Supplementation of betaine hydrochloride completes the cycle of methionine metabolism
  • Appropriate for all individuals with high risk of developing atherosclerosis and heart disease
  • Appropriate for all individuals with NIDDM whose risk of CVD is inherently increased

  • Amount Per Serving:

    Vitamin B6.......120 mg (as pyridoxine hydrochloride: pyridoxal-5-phosphate 5:1) Folic acid.......5 mg Vitamin B12.......6000 mcg (as methylcobalamin) Betaine hydrochloride.......1000 mg

    Other Ingredients: Cellulose, silica, vegetable magnesium stearate.

    Recommended Use: 1-2 capsules taken daily with a meal or as professionally directed.

    Contra-indications: Avoid during pregnancy and while breast feeding. Keep out of reach of children.

    Homocysteine is an amino acid by-product of methionine metabolism. Elevated plasma levels of homocysteine are now recognized independent risk factors for coronary artery disease, cerebrovascular disease and peripheral vascular disease. The quantitative increase in risk for developing these diseases is approximately 1.5 times for an increase in total plasma homocysteine level of 5mmoles (Beresford & Boushey, 2001). There is a possible causal relationship between increased homocysteine level and increased risk of CVD in that homocysteine may induce oxidation of LDL particles and also alteration of the endothelial lining, making it more prone to accumulation of fatty plaques.

    Using Vitamins To Reduce Homocysteine Levels The accumulation of homocysteine in normal individuals is now linked to the deficiency of the B vitamins, folic acid, vitamin B12 and vitamin B6. As the Figure below shows, all of these are ultimately associated in methionine metabolism. Numerous studies have now shown that supplementation of these compounds with the addition of betaine is consistently able to lower homocysteine levels in the majority of individuals. Folate is the most important of these nutrients and when supplemented alone is able to lower homocysteine. However, the difference is greater and more consistent when complemented with the other nutrients.

    Key Enzymes: N-5-methyltetrahydrofolate: homocysteine methyltransferase (methionine synthase) Betaine: homocysteine methyltransferase Methylene-tetrahydrofolate reductase (MTHFR) Cystathionine b-synthase Gamma-cystathionase
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    *Statements made here have not been evaluated by the U.S. Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease. As with any dietary or nutritional supplement, consult your healthcare practitioner before using natural health products, especially if you are pregnant, nursing, or under medical supervision.

    Disclaimer: Renewal Enterprises does not make claims to consumers in support of health benefits derived from nutritional supplements, vitamins, herbs, diet, or foods. This means we cannot make specific statements as to how nutritional supplements, vitamins, herbs, or diet may help to prevent or treat diseases. Taking natural health products, including recommendations from nutritional consultations, should be a decision based on education and personal research.